Quinolines and derivatives
- (1)
- (1)
- (1)
- (219)
- (6)
- (40)
- (2)
- (12)
- (47)
- (1)
- (37)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (7)
- (132)
- (1)
- (9)
- (16)
- (1)
- (35)
- (1)
- (1)
- (1)
- (1)
- (1)
- (189)
- (1)
- (1)
- (15)
- (1)
- (17)
- (17)
- (7)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (7)
- (22)
- (26)
- (30)
- (4)
- (6)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (6)
- (5)
- (2)
- (1)
- (11)
- (1)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (25)
- (16)
- (2)
- (3)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (4)
- (4)
- (8)
- (2)
- (1)
- (2)
- (1)
- (1)
- (6)
- (2)
- (1)
- (1)
- (2)
- (1)
- (6)
- (1)
- (20)
- (1)
- (5)
- (1)
- (3)
- (5)
- (1)
- (2)
- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (1)
- (2)
- (5)
- (2)
- (4)
- (2)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (4)
- (1)
- (1)
- (3)
- (3)
- (1)
- (7)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (13)
- (1)
- (2)
- (2)
- (4)
- (3)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (19)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (4)
- (5)
- (1)
- (2)
- (1)
- (1)
- (2)
- (4)
- (3)
- (2)
- (1)
- (9)
- (2)
- (3)
- (3)
- (2)
- (5)
- (3)
- (13)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (4)
- (5)
- (4)
- (3)
- (3)
- (7)
- (1)
- (2)
- (3)
- (7)
- (5)
- (2)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (4)
- (2)
- (2)
- (6)
- (2)
- (7)
- (4)
- (3)
- (2)
- (2)
- (5)
- (2)
- (1)
- (14)
- (1)
- (1)
- (23)
- (42)
- (24)
- (18)
- (83)
- (3)
- (17)
- (3)
- (5)
- (8)
- (1)
- (6)
- (1)
- (5)
- (1)
- (6)
- (5)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (4)
- (1)
- (26)
- (19)
- (70)
- (110)
- (3)
- (1)
- (2)
- (59)
- (5)
- (1)
- (1)
- (2)
- (299)
- (2)
- (2)
- (4)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (3)
- (9)
- (3)
- (2)
- (62)
- (2)
- (29)
- (3)
- (1)
- (1)
- (3)
- (3)
- (2)
- (1)
- (2)
- (1)
- (5)
- (4)
- (2)
- (1)
- (3)
- (1)
- (2)
- (2)
- (5)
- (3)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (4)
- (1)
- (5)
- (3)
- (5)
- (2)
- (2)
- (3)
- (2)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
Filtered Search Results
Apexbio Technology LLC Amorolfine HCl 78613-38-4 200mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Amorolfine hydrochloride (78613-38-4) is a small-molecule inhibitor targeting 14-reductase and 7 8-isomerase enzymes essential for fungal ergosterol synthesis It is designed to disrupt fungal sterol biosynthesis thereby impairing membrane stability and fungal cell viability Amorolfine hydrochloride exerts its biological activity primarily through inhibition of 14-reductase and 7 8-isomerase In in vitro studies Amorolfine hydrochloride demonstrates antifungal activity with IC50 values ranging from approximately 0 02 to 0 5 g/mL depending on fungal species and experimental conditions Based on these pharmacological properties Amorolfine hydrochloride holds research potential in investigating antifungal activity against fungal pathogens including models of human nail infection
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC RU.521 2262452-06-0 5mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
RU 521 (CAS 2262452-06-0) is a selective inhibitor of cyclic GMP-AMP synthase (cGAS) an enzyme responsible for synthesizing cGAMP upon recognition of cytosolic double-stranded DNA By interfering with cGAS-mediated cGAMP production RU 521 suppresses activation of the type I interferon signaling pathway Experimental studies demonstrate that RU 521 reduces cGAS-dependent signal transduction and interferon responses in reporter assays containing double-stranded DNA In macrophages derived from Aicardi-Gouti res syndrome mouse models RU 521 lowers basal interferon expression This compound is a valuable tool for investigating cGAS-dependent innate immune pathways
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC PIK-294 900185-02-6 200mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PIK-294 (CAS 900185-02-6) is a potent and highly selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) isoform p110 with an IC50 of 10 nM It exhibits substantially reduced activity against PI3K PI3K and PI3K demonstrating a 1 000-fold 49-fold and 16-fold lower potency respectively Biochemical studies indicate that PIK-294 interacts with a high-affinity pocket in the ATP-binding site contributing to its inhibitory properties in vitro Used as a chemical probe PIK-294 aids in delineating isoform-specific PI3K functions such as the distinct roles of PI3K isoforms in insulin signaling and cellular differentiation pathways No clinical studies have been reported
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Tamibarotene | 94497-51-5 | 99.57% | 351.44 | 200 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Tamibarotene is an orally active retinoic acid receptor α (RARα) agonist, demonstrating high selectivity over RARγ. It is intended for research use only.
- Orally active retinoic acid receptor α (RARα) agonist
- High selectivity over RARγ
- Suitable for research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC Cefotiam hydrochloride 200MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 10 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted. Purity 98.74%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 7-Methoxy-4(1H)-quinolinone | 82121-05-9 | 1G
Chem-Impex | 7-Methoxy-4(1H)-quinolinone | 1G | 82121-05-9 | MFCD07369800 | MW:172.57
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules METHYL 2-QUINOLIN-6-YLAC 10G
5000169155 METHYL 2-QUINOLIN-6-YLAC 10G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Carboplatin | 41575-94-4 | 99.9% | 371.25 | 200 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Carboplatin (NSC 241240) is a DNA synthesis inhibitor that works by binding to DNA, which in turn inhibits replication and transcription, ultimately inducing cell death. It is a derivative of CDDP and is considered a potent anti-cancer agent.
- DNA synthesis inhibitor
- Binds to DNA
- Inhibits replication and transcription
- Induces cell death
- Derivative of CDDP
- Potent anti-cancer agent
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000378171 STF-083010 200MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC N2-Methylguanosine 5MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. N2-Methylguanosine is a modified nucleoside found at several specific sites in various tRNAs. Purity 98%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
TARGETMOL CHEMICALS INC Squalene 200MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Squalene (AddaVax) is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran, wheat germ, and olives. All higher organisms produce squalene, including humans. Squalene is an intermediate product in the synthesis of cholesterol and shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Purity 99.33%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | MFCD00006766 | 144.17 | 1 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
2-Aminoquinoline (2-Quinolinamine) is a promising compound being researched for its potential as an antineurodegenerative agent. It exhibits antiviral activity against the vaccinia virus. While it acts as a bioavailable nNOS inhibitor, it shows low human nNOS inhibition and limited selectivity against human eNOS, and it significantly binds to other CNS targets.
- Acts as a bioavailable nNOS inhibitor
- Exhibits antiviral activity against vaccinia virus
- Potential for research into antineurodegenerative agents
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 5-METHOXY-8-QUINOLINOL | 57334-35-7 | MFCD18414704 | 1g
AstaTech | 5-METHOXY-8-QUINOLINOL | 1g | 273172844 | 76306 | 95.000 | 57334-35-7 | MFCD18414704 | 175.187 | C10H9NO2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000383875 VII-31 10MM 1ML
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Lobeglitazone sulfate | 763108-62-9 | 99.6% | 578.61 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Lobeglitazone sulfate is a novel thiazolidinedione and an orally active agonist for PPAR with EC50 values of 137.4 nM for PPARγ and 546.3 nM for PPARα. It acts as an inhibitor for the ERK/JNK/Smad/NF-κB signaling pathway.
- Exhibits anti-inflammatory, anti-diabetic, anti-fibrotic, and anti-atherosclerotic properties.
- Increases glucose uptake in 3T3-L1 adipocytes and L6 muscle cells.
- Inhibits NO generation and pro-inflammatory cytokines in LPS-stimulated BMDMs.
- Inhibits TGF-β1-induced expression of α-SMA and fibronectin, showing anti-fibrotic properties.
- Inhibits PDGF-induced proliferation and migration of vascular smooth muscle cells.
- Demonstrates anti-atherosclerotic property in ApoE-/- mouse aortic atherosclerosis models.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More